Acetaminophen (APAP) is not only included in over-the-counter drugs like Tylenol, Excedrin, Midol, Nyquil, Sudafed, Robitussin, and Alka-Seltzer Plus, while it leads to roughly fifty-six thousand (56,000) emergency-room visits and two thousand and six hundred (2,600) hospital admissions, every year, as it links to almost half (50%) of all acute liver-failure cases, and it contributes to roughly twenty percent (20%) of liver transplants, in America.
But there’s so much more….
The White House has issued a press release warning that acetaminophen use in pregnant women, especially in the third trimester, may cause long-term neurological effects in their unborn children.
The response of the main-stream media, which relentlessly advertises pharmaceuticals, is to attack the assertion, since it wants pregnant women to take their chances.
But the Food and Drug Administration (FDA) did a review of twenty-four (24) studies, which found associations between acetaminophen, pregnancy, and neurobehavioral outcomes, as it redacted parts of its report (including a suggested precautionary measure).
And an earlier review of the drug, by the same federal agency, found that “its use during pregnancy is not necessarily completely benign for the fetus,” so “[i]t would be desirable for the agency to communicate this message to healthcare providers and pregnant women.”
This built on a peer-reviewed article, reviewing nine (9) peer-reviewed studies, showing that the use of paracetamol (acetaminophen) among pregnant women had a possible association with neurodevelopmental outcomes in their children, which included autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), and lower intelligence (IQ).
Plus, there was a peer-reviewed study of more than sixty thousand (64,322) children and mothers that showed an increased risk and incidence of hyperkinetic disorder (HKD) and attention deficit hyperactivity disorder (ADHD).
Plus, there was a peer-reviewed study that went deeper into the science, relying not on maternal self-report but on measurements of cord plasma acetaminophen metabolites, so it concluded that fetal exposure to the drug was associated with significantly increased risk of childhood attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD).
Plus, there was a peer-reviewed consensus statement finding that “increasing experimental and epidemiological research suggests that prenatal exposure to APAP [acetaminophen] might alter fetal development, which could increase the risk of some neurodevelopmental, reproductive, and urogenital disorders” so that “pregnant women should be cautioned at the beginning of pregnancy to forego [the drug].”
Plus, there was a peer-reviewed evaluation that stated “[n]umerous well-designed studies have indicated that pregnant mothers exposed to acetaminophen have children diagnosed with neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), at higher rates than children of pregnant mothers who were not exposed to acetaminophen,” so that “immediate steps should be taken to advise pregnant women to limit acetaminophen consumption to protect their offspring’s neurodevelopment.”
All of this led to ongoing federal litigation against Johnson & Johnson Consumer Inc. (JJCI), the manufacturer of Tylenol, and associated retailers, for failure to warn mothers of the dangers of acetaminophen, as it caused their children to acquire autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD).
So, the Food and Drug Administration (FDA) has initiated a safety label change for acetaminophen to reflect evidence suggesting that its use by pregnant women may be associated with an increased risk of neurological conditions, such as autism, in their children.
And the government sent an accompanying letter warning physicians of the same dangers.
But what would they know?
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